Prevalence of canine cutaneous neoplasms from Shiraz, Iran

Document Type : Research Articles

Authors

Shiraz University

Abstract

The present study was conducted on 42 dogs with a histopathological diagnosis of skin neoplasia presented in the Shiraz University Veterinary Clinic from April 2012 to December 2017. All cases were reviewed, excluding the mammary gland neoplasms. The histopathological type, prevalence, sex, age, breed and site distribution of the neoplasms were described. In addition, previous studies on canine skin tumors from other geographic regions were evaluated and compared with the results of the present study. Fifteen different histopathological types of tumor were diagnosed. The prevalence of epithelial, mesenchymal, melanocytic and lymphohistiocytic tumors was 61.9%, 35.7%, 2.4% and 0%, respectively. Th e three most common tumors were sebaceous gland adenoma (21.42%), squamous cell carcinoma (11.9%), and lipoma (11.9%). The incidences of these tumors were more than other researches. Although there is no obvious explanation for these geographical differences, the possible reasons may be the geographical locations, environmental infl uences, and the study population and breed. Terriers were the most common type of the dogs in this study (34.4%). The present findings about the dogs age and various skin tumors and the anatomical locations indicates that there is no signifi cant variation in these important parameters among the Iranian dogs and dogs from other parts of the world.

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Main Subjects


1. Anudep R, Boonmee S, Lek O, Sailasuta A, Th anawongnuwech
R and Teankum K. Neoplasms of dogs in Bangkok.
Th ai. J. Vet. Med. 2003 33(1): 60–66.
2. Murphy S. Skin neoplasia in small animals. Common canine
tumours. In Practice. 2006; 28(7): 398–402.
3. Graf R, Pospischil A, Guscetti F, Meier D, Welle M and Dettwiler
M. Cutaneous Tumors in Swiss Dogs: Retrospective
Data From the Swiss Canine Cancer Registry, 2008–2013. Vet.
Pathol. 2018; DOI: 10.1177/0300985818789466.
4. Bostock DE. Neoplasms of the skin and subcutaneous tissues
in dogs and cats. Brit. Vet. J. 1986; 142: 1–19.
5. Brodey RS. Canine and feline neoplasia. Adv. Vet. Sci. Comp.
Med. 1970; 14: 309-354.
6. Kaldrymidou H, Leontides L, Koutinas AF, Saridomichelakis
MN and Karayannopoulou M. Prevalence, distribution and
factors associated with the presence and the potential for malignancy
of cutaneous neoplasms in 174 dogs admitted to a
clinic in northern Greece. J. Vet. Med. 2002; 49(2): 87–91.
7. Chikweto A, McNeil P, Bhaiyat MI, Stone D and Sharma
RN. Neoplastic and Nonneoplastic Cutaneous Tumors
of Dogs in Grenada, West Indies. ISRN Vet. Sci. 2011;
DOI:10.5402/2011/416435: 1–6.
8. Mukaratirwa S, Chipunza J, Chitanga S, Chimonyo M and
Bhebhe E. Canine cutaneous neoplasms: prevalence and infl
uence of age, sex and site on the presence and potential malignancy
of cutaneous neoplasm in dogs from Zimbabwe. J. S.
Afr. Vet. Assoc. 2005; 76(2): 59–62.
9. Pandey GS, Sharma RN and Chizyuka HGB. Study of neoplasms
of dogs in Zambia. Bull. Anim. Health. Prod. Afr.
1983; 31: 71-73.
10. Reddy GBM, Kumar R, Kumar P, Sharma AK and Singh ND.
Canine skin tumours: occurrence and histopathology. Indian
J. Vet. Pathol. 2009; 33(2): 200–203.
11. Pakhrin B, Kang MS, Bae IH, Park MS, Jee H, You MH, Kim
JH, Yoon BI, Choi YK and Kim DY. Retrospective study of
canine cutaneous tumors in Korea. J. Vet. Sci. 2007; 8(3): 229-
236.
12. De Souza TM, Fighera RA, Irigoyen LF and De Barros CSL.
Retrospective study on 761 canine skin tumors. Cienc. Rural.
2006; 36(2): 555–560.
13. Hargis AM, Ihrke PJ, Spangler WL and Stannard AA. A retrospective
clinicopathologic study of 212 dogs with cutaneous
hemangiomas and hemangiosarcomas.
Vet. Pathol. 1992; 29(4): 316–
328.
14. Nikula KJ, Benjamin SA, Angleton
GM, Saunders WJ and Lee AC. Ultraviolet
radiation, solar dermatosis, and
cutaneous neoplasia in beagle dogs.
Radiat. Res. 1992; 129(1): 11-18.
15. Er JC and Sutton RH. A survey of skin
neoplasms in dogs from the Brisbane
region. Aust. Vet. J. 1989; 66(7): 225–
227.
16. Vail DM and Withrow SJ. Tumors of
the skin and subcutaneous tissues. In:
Withrow SJ, MacEwen EG, editors.
Small Animal Clinical Oncology. 3rd
ed. Philadelphia, Saunders; 2001; P:
233-260.
17. Goldschmidt MH and Hendrick MJ.
Tumors of the skin and soft tissues. In:
Meuten DJ, editor. Tumors in Domestic
Animals. 4th ed. Iowa State Press,
Ames; 2002; P: 45-117.
18. Scott DW, Miller WT and Griffi n CE.
Small Animal Dermatology. 7th ed.
Missouri, Elsevier; 2013; P: 774-825.
19. Schneider R. Tumors in domestic animals.
2nd ed. University of California
Press, Berkeley, USA; 1978.
20. Sharif MAM. Epidemiology of skin
tumor entities according to the new
WHO classifi cation in dogs and
cats. Inaugural-dissertation. VVB
LAUFERSWEILER VERLAG, Giessen,
Germany; 2006.
21. Goldschmidt MH, Dunstan RW, Stannard
AA, Von Tscharner C, Walder EJ
and Yager JA. Histological classifi cation
of epithelial and melanocytic tumors
of the skin of domestic animals.
World Health Organization International
Classifi cation of Tumors in
Domestic Animals, vol. 3 of Second
Series, Armed Force Institute of Pathology,
Washington, DC, USA; 1998;
P: 11–101.
22. Hendrick MJ, Mahaff ey EA, Moore
FM, Vos JH, Walder EJ, Hendrick
MJ, et al. Histological classifi cation
of mesenchymal tumors of skin and
soft tissues of domestic animals. In:
World Health Organization International
Classifi cation of Tumors in
Domestic Animals, vol. 2 of Second
Series, Armed Force Institute of Pathology,
Washington, DC, USA; 1998;
P: 15–60.
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