Haemato-biochemical response to lumbar epidural anaesthesia using bupivacaine alone and in combination with certain analgesics in buffalo calves

Document Type : Research Articles

Authors

Anjora

Abstract

The present study was undertaken to evaluate the efficacy of bupivacaine alone and in combination with fentanyl and edetomidine for lumbar epidural analgesia in fifteen buffalo
calves. Haemato-biochemical parameters viz- Hb PCV, TLC, DLC, serum glucose, Serum Total protein, Serum urea nitrogen, Serum Creatinine, AST and ALT were measured after lumbar epidural administration of bupivacaine alone (group A), bupivacaine with
fentanyl (group B) and bupivacaine with medetomidine (group C) animals (@ 0.15mg/kg body wt., 0.15mg/kg body wt + 2μgm/kg body wt, 0.15mg/kg body wt.+ 15μgm/kg body wt) respectively. Haematological studies revealed a not really significant decrease in Hb, PCV and TLC in group A and B, a significant (p

Keywords


Chacko, B. (2003) Epidural effects of fentanyl citrate alone, along with local analgesic and its reversal in dogs. M.V.Sc.
Thesis, JNKVV, Jabalpur (M.P).
Ekblom, L. and Widman, B. A. (1966) Comparison of the properties of LAC-43, prilocaine and mepivacaine in extradural anaesthesia Acta Veterinaria Scandinavica Supplementum 21, 33.
Hsu, W. H. and Hummel, S. K. (1981) Xylazine induced hyperglycaemia in cattle: A possible involvement of alpha-2
adrenergic receptors regulating insulin release. Endocrinology 109, 825-829.
Jenkner, F. L. (1977) Peripheral nerve block.Wein, Springer Verlag. Newyork.Kaneko, J. J. (1989) Clinical biochemistry of
domestic animals. 4th edn. Academic press, London.
Kinjavdeker, P. (1998) Spinal analgesia with Alpha-2 agonists and their combinations with ketamine and lignocaine in goats.
Ph.D. Thesis submitted to Deemed University IVRI, Izatnagar, India.
Koichev, K., Golemanov, D., Houbenov, H.and Aminokov, B. (1988) Experimental study on the effect of “Domesedan” in sheep and cattle.Jounral of Association of Veterinary
Anaesthesist 15, 114.
Lehninger, A. L. (1990) Oxidative degradation of amino acids: The urea cycle . In:Principles of Biochemistry. Ist edn. Pp.
531-560. CBS. Publishing and Distributers Pvt. Ltd., Delhi.
Lumb, W. V. and Jones, E. W. (1996) Preanesthetics and Anesthetic Adjuncts. Veterinary Anesthesia and
Analgesia. Pp183 – 209. 3rd edn.Blackwell Publishing.
Mottelib, A. A. and El-Gindhi, M. H. (1975)Studies on buffaloes tranquilized by Rompun. Zebralter Veterinary Medicine 22 A (5), 407-413.
Pratap, K., Kinjavdekar, P. and Amarpal.(2001) Lumbosacral epidural analgesia in buffalo calves. Comparison of
xylazine and detomidine. Indian Veterinary Journal 78(3), 217-219.
Scheinin, M. and McDonald, E. (1989) An introduction to the pharmacology of alpha-2 adrenoceptors in the central
nervous system. Acta Veterinaria Scandinavica Supplementum 85,11-19.
Schumannn, D. (1990) Post operative hyperglycaemia.
Clinical benefits of insulin therapy. Heart Lung 19(20), 165-173.
Snedecor, G. W. and Cocharan, W. G. (1994) Statistical Methods. 8th edn, Pp 254-68.East West Press, New Delhi.
Soliman, M. K., Amrousi, S. E. and Khamis, M.Y. (1965) The influence of tranquilizers Haemato-biochemical response to lumbar epidural anaesthesia and barbiturate anaesthesia on the blood picture and electrolytes of dogs.Veterinary Record 77: 1256.
Thurmon, J. C., Nelson, R. D., Harsfield, S. M.and Rumore, R. A. (1978) Effects of xylazine hydrochloride on urine in cattle.
Australian Veterinary Journal 54, 178.
Tiwari, S. K., Amresh Kumar, Jadon, N. S.,Parikh, P. V. and Kumar, A. (1999) Epidural xylazine and detomidine with or
without local anaesthetics in buffaloes:haematological and biochemical changes.Indian Journal of Animal Science 69, 85-
87.
Tiwari, S. K., Kumar, A., Jadon, N. S. and Parikh, P. V. (1996) Haematological and biochemical response to epidural
xylazine or detomidine with and without local anaesthetics in buffaloes. Indian Journal of Veterinary Surgery 19, 37-38.