Unusual case of cutaneous squamous cell carcinoma in an ewe

Document Type : Short communication

Authors

• Vahid Najarnezhad ¹
• Mohammad Reza Aslani ²

¹ Department of Clinical Sciences, School of Veterinary Medicine, University of Urmia, Urmia

² Department of Clinical Sciences, School of Veterinary Medicine, University of Sharekord, Sharekord

10.22067/veterinary.v4i2.16901

Abstract

Squamous cell carcinoma (SCC) is a malignant tumor of epidermal cells in which the cells show differentiation to keratinocytes and is common in the horses, cattle, cats and dogs but is uncommon in the sheep. This communication describes a case of cutaneous squamous cell carcinoma (SCC) in a 5-year-old ewe. The tumor mass located on lumbar back and histological evaluation of biopsy sample revealed features of active SCC including atypical squamous cells with pleomorphism and hyperchromatism and atypical mitotic figures with dyskeratotic cells.

Keywords

• squamous cell carcinoma
• Sheep
• cutaneous mass
• pigmentation

20.1001.1.2008465.2012.4.2.8.0

Main Subjects

• Dermatology
• Immunology

---

References

Anderson, DE (1991). Genetic Study of Eye Cancer in Cattle. Journal of Heredity 83, 21-26.

 

Del Fava, C; Verissimo, CJ; Rodrigues, CFC; Cunha, EA; Ueda, M; Maiorka, PC and D´Angelino, JL (2001). Occurrence of squamous cell carcinoma in sheep from

a farm in Sao Paulo State, Brazil. Arquivos do Instituto Biologico Sao Paulo 68, 35-40.

 

Divers, TJ and Peek, SF (2007) Rebhun's diseases of dairy cattle. 2nd edn., Saunders & Elsevier, St. Louis, p.304.

 

Gilger, BC; Whitley, RD and McLaughlin, SA (1991). Bovine ocular squamous cell carcinoma: a review. Veterinary Annual 13, 73-84.

 

Goldschmidt, MH and Hendrick MJ (2002). Tumors of the skin and soft tissues. In Tumors in Domestic Animals, 4th edn.Eds D. J. Meuten, Iwa State Press,

Ames, pp 45-118.

 

Ladds, PW and Entwistle, KW (1977).Observation on squamous cell carcinomas of sheep in Queensland,

Australia. British Journal of Cancer 35, 110-114.

 

Ladds, PW and Daniels, PW (1982) Animal model of human disease: Squamous cell carcinoma. American Journal of Pathology 107, 122-123.

 

Lioyd, LC (1961). Epithelial tumors of the skin of sheep. British Journal of Cancer 15, 780-789.

 

Mendez, Aan; Perez, J; Ruiz-Villamor, E; Garcia, R; Martin, MP and Mozos, E (1997). Clinicopathological study of an

outbreak of squamous cell carcinoma in sheep. Veterinary Record 141, 597-600.

 

Scott, DW (1988). Large Animal Dermatology. Saunders, Philadelphia, pp. 429-431.

 

Swan, RA; Chapman, HM; Hawkins, CD; Howell, JMcC and Spalding, VT (1984). The epidemiology of squamous

cell carcinoma of the perineal region of sheep: Abattoir and flock studies. Australian Veterinary Journal 61, 146-

151.

 

Vanselow, BA and Spradbrow, PB (1983). Squamous cell carcinoma of the vulva, hyperkeratosis and papillomaviruses in a ewe. Australian Veterinary Journal

60, 194-195.