Identification of bovine ephemeral fever (BEF) outbreak in a large dairy farm in Varamin, Iran

Document Type : Research Articles

Authors

• Taghi Taghipour Bazargani ¹
• Ahmad Raza Movassaghi ²
• Ali Reza Bahonar ³
• Ebrahim Bani Hassan ¹
• Farhid Hemmatzadeh ¹
• Kamal Khedmati ⁴

¹ Universtiy of Tehran

² Ferdowsi University of Mashhad

³ FaculUniverstiy of Tehran

⁴ Razi Vaccine and Serum Reaearch Institute

10.22067/veterinary.v5i1.26529

Abstract

Bovine Ephemeral Fever (BEF) flared up in a dairy farm with 2097 animals. The disease started in September, 2006, with daily means of environmental temperature (ET) and relative humidity (RH) of 23.8 ºC and 37%, respectively, and ended after 48 days with ET and RH of 16.2 ºC and 68%, respectively. In this outbreak, the age of affected animals was above 10 months and the morbidity rate was 13.07%. Clinical signs included fever, hyperpnoea, mouth
breathing, subcutaneous emphysema and death. Histologically, there were vasculitis,hyperemia; hemorrhage and edema in soft tissues and rupture of alveolar walls. Both Culex and Colicoides spp. were captured as vectors. Bovine Ephemeral Fever virus genome was detected in blood samples by RT-PCR and the CPE was shown by blood sample culture.

Keywords

• Bovine ephemeral
• fever
• vasculitis
• subcutaneous emphysema
• pneumoperitoneum

20.1001.1.2008465.2013.5.1.5.2

Main Subjects

• Infectious diseases
• Large animal internal medicine

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References

Abu Elzein EM, Gameel AA, al-Afaleq AI, al-Gundi O, al-Bashier AM, Zeedan A, al-Mageed HA, Abu Khadra H.( 1999) ,Observations on the recent epizootic of bovine ephemeral fever in Saudi Arabia.Revue scientifique et technique 18, 672-80.

Bai WB, Jiang CL, Davis SS. (1991) Preliminary observations on the epidemiology of bovine ephemeral fever in China.Tropical Animal Health and Production 23, 22-26.

Bazarghani TT, Charkhkar S, Doroudi J and Bani Hassan E. (2006) A review on Pest des Petits Ruminants (PPR) with special reference to PPr in Iran, Journal of Veterinary Medicine B 53, 17-18.

Burgess GW, Spradbrow PB. (1977) Studies on the pathogenesis of bovine ephemeral fever. Australian Veterinary Journal 53,363-368.

Chang C. J., Shih W.L., Yu F.L., Liao M.H., Liu H.J. (2004) Apoptosis induced by bovine ephemeral fever virus, Journal of Virological Methods 122, 165-170.

Elamin MA, Spradbrow PB. (1978) Isolation and cultivation of bovine ephemeral fever virus in chickens and chicken embryos.Journal of Hygiene (Lond) 81,1-7.

Farag MA,al-Sukayran A, Mazloum KS, al-Bukomy AM. (1998) Epizootics of bovine ephemeral fever on dairy farms in Saudi Arabia, Revue scientifique et technique 17,713-22.

George TD, Standfast HA, Christie DG, Knott SG, Morgan IR. (1977) The epizootiology of bovine ephemeral fever in Australia and Papua-New Guinea, Australian Veterinary Journal 53, 17-28.

Hall WT,Daddow KN, Dimmock CK, George TD, Standfast HA. (1975) The infection of merino sheep with bovine ephemeral fever virus. Australian Veterinary Journal 51, 344-346.

Hazrati A., Hessami Ghajar M., Roustai M.H. and Dayhim F. (1974) Bovine ephemeral fever. Proceedings of the 11th Regional Seminar of the National Veterinary Organization, Shiraz-Iran, pp.327-351.

Hertig C, Pye AD, Hyatt AD, Davis SS,McWilliam SM, Heine HG, Walker PJ,Boyle DB. (1996) Vaccinia virus expressed bovine ephemeral fever virus G but not G(NS) glycoprotein induces neutralizing antibodies and protects against experimental infection. Journal of General Virology 77 ( Pt 4), 631-640.

Hsieh YC, Chen SH, Chou CC, Ting LJ, Itakura C, Wang FI. (2005) Bovine ephemeral fever in Taiwan (2001-2002). Journal of Veterinary Medical Science 67,411-416.

Hsieh YC, Chen SH, Huang,J-Y, LeeY-F, Tsai K-Y, Liu, H-J. (2005) Virus identification and serum antibody monitoring of bovine ephemeral fever in Tainan county during 2002-2004. Taiwan Veterinary Journal 31, 208-216.

Hsieh YC, Wang SY, Lee YF, Chen SH, Mak PO, Chu CY. (2006) DNA sequence analysis of glycoprotein G gene of bovine ephemeral fever virus and development of a double oil emulsion vaccine against bovine ephemeral fever. Journal of Veterinary Medical Science 68, 543-548.

Kirkland PD. (2002) Akabane and bovine ephemeral fever virus infections. Veterinary Clinics of North America:Food Animal Practice 18,501-514.

Grant Maxie M. JUbb (2007) Kennedy and Palmer's pathology of Domestic Animals. Vol.3, p83. SAUNDERS (Elsevier)

Nandi S, Negi BS. (1999) Bovine ephemeral fever: a review. Comparative immunology, microbiology and infectious diseases 22, 81-91.

Odiawo GO. (1989) The relationship between selenium deficiency and the development of pulmonary and subcutaneous emphysema in bovine ephemeral fever virus-infected cattle. Onderstepoort Journal of Veterinary Research 56,123-125.

Shirakawa H, Ishibashi K, Ogawa T. A. (1994) comparison of the epidemiology of bovine ephemeral fever in South Korea and south-western Japan. Australian Veterinary Journal 71, 50-52.

St George TD. (1985)Studies on the pathogenesis of bovine ephemeral fever in sentinel cattle. I. Virology and serology. Veterinary Microbiology 10, 493-504.

St George TD, Murphy GM, Burren B, Uren MF.(1995) Studies on the pathogenesis of bovine ephemeral fever. IV: A comparison with the inflammatory events in milk fever of cattle, Veterinary Microbiology 46, 131-142.

Tzipori S. (1975) The susceptibility of young and newborn calves to bovine ephemeral fever virus. Australian Veterinary Journal 51, 251-253.

Uren MF. (1989) Bovine ephemeral fever., Australian Veterinary Journal 66(8), 233-236.

Vanselow BA, Walthall JC, Abetz I. (1995) Field trials of ephemeral fever vaccines. Veterinary Microbiology 46, 117-130.

Walker PJ. (2005) Bovine ephemeral fever in Australia and the world. Current Topics in Microbiology and Immunology. 292,57-80.

Wang FI, Hsu AM, Huang KJ. (2001) Bovine ephemeral fever in Taiwan; Journal of Veterinary Diagnostic Investigation 13,462-467.

Tzipori S. (1975) The susceptibility of young and newborn calves too bovine ephemeral fever virus. Australian Veterinary Journal 51, 251-253.

Tzipori TS, Spradbrow PB, Doyle T. (1975)Laboratory and field studies with a bovine ephemeral fever vaccine; Australian Veterinary Journal 51, 244-250.

Uren MF, St George TD, Zakrzewski H. (1989) The effect of anti-inflammatory agents on the clinical expression of bovine ephemeral fever; Veterinary Microbiology 9, 99-111.

Yeruham I, Braverman Y, Yadin H, Van Ham M,Chai D, Tiomkin D, Frank D. (2002) Epidemiological investigations of outbreaks of bovine ephemeral fever in Israel. Veterinary Record 151, 117-121.

Yeruham I, Gur Y, Braverman Y. (2007)Retrospective epidemiological investigation of an outbreak of bovine

ephemeral fever in 1991 affecting dairy cattle herds on the Mediterranean coastal plain. Veterinary Journal 173, 192-195.

Yeruham I, Sharir B, Yadin H, Tiomkin D.(2003) Bovine ephemeral fever in beef cattle herds in the Jordan Valley, Israel. Veterinary Record 152, 86.

Young PL, Spradbrow PB. (1980) The role of neutrophils in bovine ephemeral fever virus infection of cattle. Journal of Infectious Diseases 142, 50-55.