Histopathological changes in experimental infestation of Paederus fuscipes in rats

Document Type : Research Articles

Authors

• Mousa Tavassoli
• Aliasghar Tehrani
• Javad Mahdavi Ghajari

Urmia University

10.22067/veterinary.v9i2.64024

Abstract

The genus Paederus consists of approximately 621 species associated with outbreaks of dermatitis. Our aim was to determine gross and microscopic changes induced by Paederus fuscipes. Adult P. fuscipes beetles were collected from infested house and then sent to laboratory. In the first group beetles were placed on the shaved parts over the shoulders of each rat. In the second group smashed insect materials were rubbed over the ear of examined animals. Gross changes after 12 hr were noticed as erythematous papules and in 72 hr the red elevated area became bigger and swollen. Microscopic examination revealed edema and mild infiltration of inflammatory cells (lymphocytes and eosinophils) after 12 hr, cell swelling and vacuolar degeneration in basal and squamous cells after 24 hr, but by 72 hr the epidermal cells were necrotic with intense accumulation of fluid and vesicles formation. Gross and microscopic changes were compared between rats exposed with squeezed beetle materials and rats exposed to live beetles. The typical gross changes were maculopapuls on the skin that histologically showed dermal edema and infiltration of lymphocytes and eosinophils.

Keywords

• Beetle
• Paederus fuscipes
• Dermatitis
• Histopathologic
• Rat

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References

1. Li XY, Zhou HZ. A review of Chinese species of the subgenus Paederus s. str. (Coleoptera: Staphylinidae: Paederinae) with description of a new species. Zootaxa. 2009; 2083:46-4.

2. Frank JH. Paederus, sensu lato (Coleoptera: Staphylinidae): An index and review of the taxa. Insecta Mundi.1988;2:97-159.

3. George AO, Hart PD. Outbreak of Paederus dermatitis in southern Nigeria. Int J Dermatol. 1990;29:500-501.

4. Lott DA, Anderson R. The Staphylinidae (rove beetles) of Britain and Ireland. Part 7 and 8: Oxyporinae, Steininae, Euaesthetinae, Pseudopsinae, Paederinae, Staphylininae. In: Handbooks for the identification of British Insects. London: Royal Entomol Society; 2011:12.

5. Triplehorn CA, Johnson NF. Borro. Long’s introduction to the study of insects. 7th ed. Belmont: Thomson-Brooks: Cole; 2005;409-11.

6. Vegas FK, Yahr MG, Venezuela C. Paederus dermatitis. Arch Dermatol Res. 1996;94:175-83.

7. Armstrong RK, Winfield JL. Paederus fuscipes dermatitis: An epidemic on Okinawa. Am J Trop Med Hygiene. 1969;18:147-50.

8. Mokhtar N, Singh R, Ghazali W. Paederus dermatitis amongst medical students in USM, Kelantan. Med J Malaysia. 1993;48:403-06.

9. Kamaladasa SD, Perera WDH, Weeratunge L. An outbreak of Paederus dermatitis in a suburban hospital in Sri Lanka. Int J Dermatol. 1997;36:34-6.

10. Nikbakhtzadeh MR, Sadeghiani C. Dermatitis caused by 2 species of Paederus in south Iran. Bulletin de la Societe de pathologie exotique.1997;92:56.

11. Zargari O, Kimyai-Asadi A, Fathalikhani F, Panahi M. Paederus dermatitis in northern Iran: a report of 156 cases. Int J Dermatol. 2003; 42:608-12.

12. Oyedeji OA, Adebami OJ, Oyedeji GA. Linear Dermatitis following contact with the rove beetle in Nigerians: a report of 2 cases. Int J Trop Med. 2009;3:6.

13. Gelmetti C, Grimalt R. Paederus dermatitis: an easy diagnosable but misdiagnosed eruption. Eur J Pediatr. 1993;152:6-8.

14. Singh G, Ali SY (2007). Paederus dermatitis. Indian J Dermatol Venereol Leprol. 2007;73:13-5.

15. Gudgel EF, Grauer FH. Acute and chronic reactions to black fly bites (Simulium fly). Arch Dermatol Syphil. 1954;70:609-15.

16. James AA, Rossignol PA. Mosquito salivary glands: parasitological and molecular aspects. Parasitol Today. 1991; 7:267-71.

17. Valenzuela JG, Charlab R, Galperin MY, Ribeiro JM. Purification, cloning, and expression of an apyrase from the bed bug Cimex lectularius: A new type of nucleotide-binding enzyme. J Biol Chem. 1998;273:30583-590.

18. Goddard J, de Shazo R. Multiple feeding by the common bed bug, Cimex lectularius, without sensitization. MidSouth Entomol. 2009;2:90-2.

19. Davalos V, Luguna-Torres VA. Uaman AEpidemic dermatitis by Paederus irritans in Piura, Peru in 1999, related to the El-nino phenomenon. Revista da Sociedade Brasileira de Medicina Tropical. 2002;35:23–8.

20. Ahmed MS, Boraei HA, Rakha OM. Histopathological characterization of induced Paederus dermatitis caused by Egyptian rove beetles (Paederus alfierii). Beni-Suef Univ J Appl Sci. 2013;2:108 -13.

21. Tavassoli M, Tabatabaei M, Mohammadi M, Esmaeilnejad B, Mohamadpour H. PCR-based Detection of Babesia spp. Infection in Collected Ticks from Cattle in West and North-West of Iran. J Arthpod Borne Dis. 2013;7:132– 38.

22. Tavassoli E, Zare S, Ghaderi Pakdel F, Tehrani AA, Tavassoli M. Histopathological Features of Ornithodoros lahorensis Bite on Rat. Iran J Parasitol. 2007;2:17-24.