Relationship between fructusamine, glucose, total protein, and albumin concentrations of serum in late pregnancy and early lactation of dairy Saanen goat

Document Type : Research Articles

Authors

Ferdowsi University of Mashhad

Abstract

The changes in serum fructosamine concentration of dairy Saanen goats during late pregnancy and early lactation and its relationship to serum glucose, total protein, and albumin concentrations was investigated. Eleven Saanen goats were selected for the study. Blood samples were collected by the jugular vein in 30, 15 and 7 days before the expected time of parturition (D-30, D-15, and D-7, respectively) and also 12 hours and 3, 7, 13, and 42 days post-partum (H+12, D+3, D+7, D+13, and D+42, respectively). The serum concentrations of fructosamine, glucose, albumin, and total protein were measured. The maximum concentration of fructosamine was at 12 hours post-partum and decreased thereafter. Serum concentration of glucose significantly increased from D-15 up to 12 hours post-partum and then decreased and stayed at the same level. The serum concentrations of albumin and total protein significantly increased during post-partum period. There were significant correlations between fructosamine and glucose concentrations at post-partum period and overall time of the study. Linear regression analysis between each sampling amount of glucose and three consecutive fructosamine concentrations revealed significant positive correlation between glucose of each sampling time with the fructosamine of first sampling time thereafter. According to the correlation between glucose and fructosamine amounts during the study, especially post-partum period in Saanen goat, fructosamine measurement could be used as a useful indicator of energy economy and probably stress in Sannen goat; but controversy between reports in ruminants needs further studies for better understanding of fructosamine as energy biomarker in ruminants.

Keywords

Main Subjects

References

Herdt T.: Ruminant adaptation to negative energy balance influences on the etiology of ketosis and fatty liver. Vet. Clin. North. Am. Food. Anim. Pract., 2000, 16, 215-230.
Nazifi S., Saeb M., Asadzade S.: Serum concentration of lipids, lipoproteins and β hydroxybutyrate in iranian native goats in late pregnancy, at parturition and during the post parturition period. Journal of Faculty Veterinary Medicine University Tehran., 2003, 58, 211-215 (In Farsi)
Radostits O.M., Clive C.G., Kenneth W.H., Constable P.D.: Veterinary Medicine: A text book of the diseases of cattle, Horses, sheep, pigs and goats. 10 th Edition. Saundres Ltd. 2007
Loste A., Marca M.C., Perez M., Unzueta A.: Clinical Value of Fruc Measurements in Non healthy dogs. Vet. Res. Commun., 2001, 25,109-15.
Kaneko J.J.: Carbohydrate metabolism and its diseases In: Kaneko J.J., Harvey J.W., Bruss M.L (Eds), Clinical Biochemistry of Domestic Animals, 6rd edn. Academic Press, San Diego, 2008, pp. 45–80.
Coppo J.A.: Evalution of fructosaminaemia and glucaemia during the growth of unweaned and early weaned half-bred zebu calves. Vet. Res. Commun., 2001, 25, 449-59.
Eckersal P.D.: Proteins, proteomics, and dysproteinemias. In: Kaneko J.J., Harvey J.W., Bruss M.L (Eds), Clinical Biochemistry of Domestic Animals, 6rd edn. Academic Press, San Diego, 2008, pp. 117–155.
Thoresen S.I., Bredal W.P.: An evaluation of serum Fruc as amarker of the duration of hypoproteinaemic conditions in dogs. Vet. Res. Commun., 1998, 22, 167-177.
Denis A.E., Richard W.N., Claudia E.R.: Comparison of serum Fruc and blood glycosylated hemoglobin concentration for assessment of glycemic control in cats with diabetes mellitus. J. Am. Vet. Med. Asso., 1999, 214,1794-1798.
Filipović N., Stojević Z., Prvanović N.: Serum Fruc concentrations in relation to metabolic changes during late pregnancy and early lactation in mares. Berliner Und Münchener Tierärztliche Wochenschrift., 2010, 123, 116–173.
Jensen A.L., Petersen M.B., Houe H.: Determination of Fruc concentration in bovine serum samples. J. Vet. Med. A., 1993, 40,111-117.
Sorondo M.L., Cirio A.: Evaluation of the serum Fruc test to monitor plasma Glu concentration in the transition dairy cow. J. Dairy Res., 2009, 76, 173-178.
Sorondo M.L., Cirio A.: Evaluation of the serum Fruc test to monitor plasma Glu concentration in the late-pregnant sheep. Anim. Prod. Sci., 2011, 51, 662-666.
Jensen A.L., AAES H.: Reference interval and critical difference for canine serum Fruc concentration. Vet. Res. Commun., 1992, 16, 317-325.
Kawamoto M., Kaneko J.J., Heusner A.A., Feldman E.C., Koizumi I.: Relation of Fruc to serum protein, Alb and Glu concentrations in healthy and diabetic dogs. Am. J. Vet. Res., 1992, 53, 851-855.
Loste A., Marca M.C.: Study of the effect of total serum protein and Alb concentrations on canine Fruc concentration. Can. J. Vet. Res., 1999, 63, 138-141.
Filipović N., Stojević Z., Masek T., Mikulec Z., Prvanović N.: Relationship between Fruc with serum protein,Alb and Glu concentrations in dairy ewes. Small. Rum. Res., 2011, 96, 46-48.
Cantley C.E., Ford D.M., Heath M.F.: Serum Fruc in ovine pregnancy toxemia: a possible prognostic index. Vet. Rec., 1991, 128, 525-526.
Mostafavi M., Seifi H.A., Mohri M., Jamshidi A.: Evaluation of Fruc as a new biomarker for diagnosis of hepatic lipidosis in dairy cows. Anim. Prod. Sci., 2015, 55, 1005-1010.
Coppo J.A., Mussart de coppo N.B.: La glicosilacion de proteinas hematicas como evaluacion retrospective de la glucemia. Aplicaciones en medicina veterinaria. Rev. de. Med. Vet., 1997, 78, 292-295.
Jensen A.L.: Various protein and Alb corrections of the serum Fruc concentration in the diagnosis of canine diabetes mellitus. Vet. Res. Commun., 1993, 17, 13-23.
NRC (National Research Council).: Nutrient requirements of small ruminants, sheep, goats, cervids, and new world camelids. The National Academic press, Washington DC, USA. 2007.
Send comment about this article
CAPTCHA Image

Files

History

  • Receive Date: 07 June 2017
  • Accept Date: 07 June 2017

Share

How to cite

Statistics