TY - JOUR ID - 30704 TI - Effect of Aloe vera and Salvia officinalis extract supplemented diet on hematology, histopathology, and hypoxia resistance in rainbow trout JO - Iranian Journal of Veterinary Science and Technology JA - IJVST LA - en SN - 2008-465X AU - Tafi, Ali Akbar AU - Meshkini, Saeed AU - Tukmechi, Amir AU - Alishahi, Mojtaba AU - Noori, Farzaneh AD - Department of Fisheries, Faculty of Natural Resources, Urmia University, Urmia, Iran AD - Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran AD - Department of Microbiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran AD - Department of Clinical Science, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran AD - Department of Aquaculture, Artemia & Aquaculture Institute, Urmia University, Urmia, Iran Y1 - 2019 PY - 2019 VL - 11 IS - 2 SP - 59 EP - 68 KW - Oncorhynchus mykiss KW - Herbal Extracts KW - Environmental stresses KW - Hematology KW - histopathology DO - 10.22067/veterinary.v11i2.81124 N2 - This study investigated the effects of Aloe vera and Salvia officinalis extracts on hematological and haemato-biochemical parameters, histopathology, and resistance against hypoxia stress in Oncorhynchus mykiss. The rainbow trout (10 ± 0.1 g) were fed seven different diets supplemented with 0% (control), 0.5%, 1% and 1.5% of A. vera or S. officinalis extract for 30 days. The feeding in all treatments was continued for 2 weeks using control diet. The fish blood samples were collected on days 30th and 45th, and total red blood cells, hematocrit and hemoglobin were measured. The glucose and cortisol of serum were examined just before and one hour after hypoxia stress (3 mg L-1) at days 30th and 45th. The gill tissue samples were taken from all treatments for histopathological study at the end of experimental period. The S. officinalis (0.5%) treated group showed a significant increase (p< 0.05) in red blood cells, hematocrits and hemoglobin compared to control group. While the A. vera (1 and 1.5%) treatments revealed significant increase in hematocrit and hemoglobin concentration compared to the control group (p< 0.05). Moreover the glucose and cortisol levels of serum were increased significantly only in S. officinalis (0.5%) treated group after hypoxia stress on days 30th and 45th compared to the control group (p< 0.05). No serious histopathological changes were observed in any treatments and control group. Based on the results obtained, dietary S. officinalis (0.5%) hydroethanolic extract improved the haematological and haemato-biochemical parameters and increased the rainbow trout resistance against hypoxia stress. UR - https://ijvst.um.ac.ir/article_30704.html L1 - https://ijvst.um.ac.ir/article_30704_a7847de3b8b345e7fdeb2e9f7019f284.pdf ER -