Central interaction of ascorbic acid and D2 dopamine receptors on spatial learning and memory in adult male rats
Sima
Nasri
Payam Noor University of Tehran
author
Mehri
Bahaaddini
Taalim and Tarbiat Colledge of Kerman
author
mehdi
abbasnejad
Shahid Bahonar University
author
Saeed
Esmaeili-Mahani
Shahid Bahonar University of Kerman, Iran
author
Ramin
Raoof
Shahid Bahonar University of Kerman
author
text
article
2014
eng
Previous studies had reported that extracellular levels of ascorbic acid have modulatory effects on dopamine receptors. Both ascorbic acid and dopamine receptor have an important role in learning and memory processes. However, the central interaction between ascorbic acid and dopamine D2 receptor on spatial learning and memory has not yet been elucidated.All experiments were carried out on male Wistar rats. Animals were subjected to 5 days of training in the Morris water maze (MWM) task; 4 days with an invisible platform to test special learning and the 5th day with a visible platform to test motivation and sensorimotor coordination.The data showed that ascorbic acid (25 µg, i.c.v.) could improve spatial learning and memory indices. Administration of bromocriptine, a D2 agonist, increased the effect of ascorbic acid, while treatment with the selective D2 antagonist sulpiride resulted in prevention of the ascorbate-induced memory consolidation. These results indicate that dopamine D2 receptors may be involved in ascorbic acid-induced learning and memory impairment.
Iranian Journal of Veterinary Science and Technology
Ferdowsi University of Mashhad
2008-465X
6
v.
1
no.
2014
1
15
https://ijvst.um.ac.ir/article_27092_ba247b32e4083846ebb729a954392019.pdf
dx.doi.org/10.22067/veterinary.v6i1.23148
Skin colonization by Malassezia species in healthy neonatal calves and their dams
Fatemeh
Ahmadi
Ferdowsi University of Mashhad
author
Samaneh
Eidi
Ferdowsi University of Mashhad,Mashhad,Iran
author
Hesam A.
seifi
Ferdowsi University of Mashhad
author
text
article
2014
eng
The aim of this study was to assess skin colonization by Malassezia species in full-term healthy newborn calves and their dams. Two hundred samples from the skins and ears of 50 neonatal calves and their dams were examined on two occasions, first and fourth weeks after birth. All of the samples were determined by cytological examination and fungal culture. The isolated yeasts were identified for Malassezia spp. using the conventional techniques based on the morphological and physiological characteristics. All the samples included in the first and fourth weeks showed typical Malassezia cells on cytological examination. Colonization with Malassezia species was obtained in 11.5% of neonatal calves and their dams. The most commonly isolated species in neonates with culture-positive results was M. pachydermatis (68.75%), followed by M. sympodialis (12.5%), M. furfur (6.25%), M. globosa (6.25%) and M. slooffiae (6.25%).The most commonly isolated species in dams with culture-positive results was M. pachydermatis (85.71%), followed by M. furfur (14.3%). This study confirms that Malassezia colonization of the skin begins at the first week of life. A high prevalence of M. pachydermatis in neonates is noted from first week. Environmental factors and maternal contact probably affect this colonization, but neonatal skin characteristics are probably important.
Iranian Journal of Veterinary Science and Technology
Ferdowsi University of Mashhad
2008-465X
6
v.
1
no.
2014
16
22
https://ijvst.um.ac.ir/article_27127_05e03ab304521dd5751a187c407ca5d2.pdf
dx.doi.org/10.22067/veterinary.v6i1.20752
A molecular (PCR) survey on abortions caused by Campylobacter spp. in sheep flocks located on the suburb of Tabriz
Samaneh
Fallah
University of Tabriz
author
hossein
hamali
University of Tabriz
author
Raziallah
Jafari Joozani
University of Tabriz
author
Payman
Zare
University of tabriz
author
Gholamreza
Norsaadat
Tabriz Veterinary Network
author
text
article
2014
eng
Campylobacteriosis is an important infectious disease of animals and humans caused by the pathogenic Campylobacter species. A total number of 132 aborted sheep fetuses and related placentas were admitted to the large animal clinic at the University of Tabriz, from October 2010 to March 2011. Tissue samples were collected from several fetal organs including liver, brain, kidney, lung, spleen, heart, stomach fluid and placenta, then separately pulverized under liquid nitrogen and finally stored at -20°C until DNA extraction. Of 132 submissions (fetuses and placentas), 12 (9.09%) and 2(1.51%) samples were diagnosed positive to the Campylobacter fetus subsp. fetus and Campylobacter jejuni by the PCR protocol, respectively. No samples were positive for Campylobacter coli.
Iranian Journal of Veterinary Science and Technology
Ferdowsi University of Mashhad
2008-465X
6
v.
1
no.
2014
23
29
https://ijvst.um.ac.ir/article_27144_5f4b0a264157a85e06eefb35acbf1ffc.pdf
dx.doi.org/10.22067/veterinary.v6i1.23248
Detection of antibiotic residues in poultry carcasses in Mashhad poultry abattoir
Farideh
Ghasemi
Ferdowsi University of Mashhad
author
Behrooz
Fathi
Ferdowsi University of Mashhad
author
Abdollah
Jamshidi
Ferdowsi University of Mashhad
author
text
article
2014
eng
In poultry breeding, use of any antibiotics as a food additive that promotes growth, prevention or treatment of infectious diseases will increase the chance of drug residues in poultry meat products. In this study, the presence of different antibiotics in ten broiler flocks, which were later transported to Mashhad poultry abattoir have been investigated, using four plate test (FPT) method. A total of one hundred breast muscle and sixty liver samples (10 breast muscles and 6 liver samples from each flock) were collected randomly. The results of this study showed, the 18.75% of samples were positive for antibiotic residues and 6.88% of samples were suspected. The results also showed that sulfonamides residue in meat and liver samples were higher than other investigated antibiotics (22% in meat and 11.7% in livers). It can be concluded that the withdrawal time of antibiotics before slaughter has been ignored in many of these farms therefore, the administration of antibiotics in poultry farms must be more rigidly controlled to prevent drug residues in food-producing animals.
Iranian Journal of Veterinary Science and Technology
Ferdowsi University of Mashhad
2008-465X
6
v.
1
no.
2014
30
36
https://ijvst.um.ac.ir/article_27180_265dea5a8e2ce6f66bc8445e02496315.pdf
dx.doi.org/10.22067/veterinary.v6i1.26316
Laxative effect of bitter almond (Amygdalus communis var. amara)
Hamid Reza
Kazrani
Ferdowsi University of Mashhad
author
Seddigheh
Jalali
Payame Noor University of Tehran
author
text
article
2014
eng
Thepossible laxative and prokinetic effects of bitter almond were studied: 1- two groups of 7 rats were gavaged with ethanol extract of bitter almond (500mg/kg) or placebo and the number of feces, fecal weight and its percentage of water were studied 18-24h thereafter. 2- Ethanol extract of bitter almond (125 or 250mg/ml), lactulose (as positive control) or placebo was randomly injected into jejuna segments in anesthetized rats (n=9). The volume of the fluid in each segment was measured after 1h. 3- Gastrointestinal (GI) transit time was studied in rats treated with the extract or placebo using phenol red. The rats were sacrificed at times 30min, 1, 2 and 4h. ethanol extract of bitter almond at 500mg/kg significantly increased fecal weight and water. It had no significant effects on the osmotic infiltration of fluid into the intestine or on the transit time of the contents in the GI tract. The current results suggest that bitter almond has a laxative effect that seems to be due to malabsorption of electrolytes and water via enterocytes.
Iranian Journal of Veterinary Science and Technology
Ferdowsi University of Mashhad
2008-465X
6
v.
1
no.
2014
37
47
https://ijvst.um.ac.ir/article_27221_5d80e9ac4812b7e3fe222ff89230d79f.pdf
dx.doi.org/10.22067/veterinary.v6i1.19398
A survey on hepatic and renal trace elements status of sheep and goats in Zarrinshahr region, Isfahan, Iran: an abattoir study
Iman
Amani
Ferdowsi University of Mashhad
author
kamran
Sharifi
Ferdowsi University of Mashhad
author
mohamad reza
aslani
University of Shahrekord
author
Abdonnaser
Mohhebi
University of Shahrekord
author
text
article
2014
eng
Hepatic and renal contents of essential trace elements provide good clues to monitor the nutritional status of grazing animals. Liver and kidney samples were collected from 60 sheep and 60 goats slaughtered in Zarrinshahr abattoirs and analyzed for essential trace elements. Hepatic Fe concentrations were significantly higher in sheep than goats. There were also higher renal and hepatic Fe concentration in age group of 2-4 year Scompared with age groups of
Iranian Journal of Veterinary Science and Technology
Ferdowsi University of Mashhad
2008-465X
6
v.
1
no.
2014
48
57
https://ijvst.um.ac.ir/article_27238_f27788be32e3c8953ea90a8bc718a844.pdf
dx.doi.org/10.22067/veterinary.v6i1.33927
The epidural analgesic effects of Meloxicam in dogs
Azin
Tavakoli
Islamic Azad University- Garmsar Branch
author
text
article
2014
eng
Epidural analgesia is an effective and frequent method used to induce analgesia in perineal region during orthopedic or obstetric procedures of pain management. 18 healthy mixed-breed dogs, were randomly divided into three groups. Lumbosacral epidural analgesia was performed in all dogs in the following order: lidocaine (0.2 mg/kg) in group A, meloxicam (0.1 mg/kg ) in group B and the combination of both drugs in group C. Heart rate, respiratory rate and body temperatures were recorded for every 5 minutes, while analgesia onset time, duration of analgesia and paralysis were also recorded in all dogs. Without any systemic complications, no significant difference was observed in mean heart rate, respiratory rate and body temperature in all groups (p>0.05). Duration of analgesia was significantly lower in group B (59 ± 15) compared to group A (109±10) and C (127± 24) (p
Iranian Journal of Veterinary Science and Technology
Ferdowsi University of Mashhad
2008-465X
6
v.
1
no.
2014
58
69
https://ijvst.um.ac.ir/article_27267_89699feb191c4f846ec2b0f99165d879.pdf
dx.doi.org/10.22067/veterinary.v6i1.18912
Case report: Follow-up, diagnosis, clinical evidence, laboratory evaluation, and treatment of Idiopathic thrombocytopenia using human Intravenous Immunglobulin in a terrier dog
Ezzatollah
Fathi
University of Tabriz, Tabriz-Iran
author
Shahram
Jamshidi
Tehran university, Iran
author
text
article
2014
eng
The aim of the present case report is to describe the outcome, hematological and biochemical changes of treatment of idiopathic thrombocytopenia in a Terrier dog using human intravenous immunglobulin. The complete blood count, serum biochemistry, indirect immunofluorescence antibody and direct coomb’s tests, radiography and sonography were performed. Laboratory findings indicated sever thrombocytopenia (
Iranian Journal of Veterinary Science and Technology
Ferdowsi University of Mashhad
2008-465X
6
v.
1
no.
2014
64
70
https://ijvst.um.ac.ir/article_27051_f5e790c0f1a024b50cada89819e17dc0.pdf
dx.doi.org/10.22067/veterinary.v6i1.22023